Tumor suppressor gene

Breakthrough in Cancer Research: New Tumor Suppression Mechanism Discovered

Scientists at St. Jude Children’s Research Hospital have discovered a novel tumor suppression mechanism involving the protein p14ARF, which interacts with nucleophosmin to inhibit ribosome production and suppress cancer cell growth. This groundbreaking research, published in Nature Communications, reveals how p14ARF’s increased expression in response to oncogenic stress can lead to significant advancements in cancer treatment strategies.

New Study Reveals 11,000 Vital Genetic Switches in Every Cell Type

Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code. New evidence challenges the simplistic view that cis-regulatory elements (CREs) are mere on/off switches for genes, emphasizing their…