Breakthrough CD7 CAR-T Cell Therapy Shows Promise for T-ALL Patients
The National University Health System in Singapore has announced groundbreaking results from a novel CAR-T cell therapy targeting CD7, offering new hope for patients with relapsed or refractory T-cell acute lymphoblastic leukaemia (T-ALL). This innovative treatment, developed in partnership with the National University of Singapore, modifies patients’ T cells to enhance immune responses against cancer cells, showing promising outcomes in clinical trials. With the potential to improve survival rates and quality of life, this therapy represents a significant advancement in precision medicine for aggressive leukaemia.
CD8 T Cells Identified as Key Indicators in Early Multiple Sclerosis Onset
Recent research highlights the crucial role of CD8-positive T cells in the early stages of multiple sclerosis (MS). Led by PD Dr. Lisa Ann Gerdes, this study, published in Science Immunology, utilized identical twins to uncover immune cell changes that may signal MS onset. The findings suggest that alterations in CD8 T cells could serve as early indicators of the disease, paving the way for new diagnostic and therapeutic strategies. Understanding these immune responses is vital for early intervention in MS, a condition that can lead to severe neurological deficits.
Promising Results in Asthma Treatment Using Engineered T Cells
Groundbreaking study in Nature Immunology shows promising results in treating asthma with engineered long-lived and multifunctional T cells. Research led by Gang Jin demonstrates durable remission of asthma in mice with a single infusion. This innovative approach offers hope for the future of asthma treatment and the potential of immunotherapy in managing respiratory diseases.
New FUME-TCRseq Technique Enables Study of Immune Response to Cancer Using Archived Tissue Samples
Researchers have developed a new technique, FUME-TCRseq, which enables the study of immune response to cancer using archived tissue samples. This breakthrough could significantly impact the understanding of the immune system’s role in cancer development, progression, and treatment.
CAR T Cells Show Potential in Treating Age-Related Diseases, Study Finds
Recent research led by Memorial Sloan Kettering Cancer Center and Cold Spring Harbor Laboratory has revealed the potential of Chimeric Antigen Receptor (CAR) T cells in treating diseases related to aging. The study suggests that these engineered immune cells could…
Breakthrough in Anti-Ageing Research
A recent breakthrough in anti-ageing research has uncovered a potential key to slowing down the ageing process, offering the prospect of a longer and healthier life. Published in Nature Aging, the study conducted by scientists in the USA has revealed…