Otoferlin

Children born deaf gain hearing in both ears through gene therapy trial

Five children born deaf now have hearing in both ears after participating in a groundbreaking gene therapy trial conducted by doctors at Fudan University in Shanghai. The trial aimed to address inherited genetic mutations hindering the body’s ability to produce a crucial protein for transmitting auditory signals. After the treatment, the children exhibited improved hearing, could locate sound origins, and comprehend speech even in noisy environments. Dr. Zheng-Yi Chen expressed astonishment at the results, noting significant progress in the children’s hearing abilities.

Baby girl born deaf hears unaided after groundbreaking gene therapy

Groundbreaking gene therapy enables baby girl born deaf to hear unaided for the first time. Opal Sandy from Oxfordshire received innovative gene therapy treatment at Addenbrooke’s Hospital in Cambridge, showing significant improvement in hearing within weeks. The therapy targeted the OTOF gene, responsible for producing otoferlin protein crucial for hearing. Results of treatment exceed expectations, offering hope for future advancements in treating hearing impairment.