Study in Nature Reveals Insights into Modulation of µ-Opioid Receptor Dynamics for Pain Management Therapeutics
A recent study published in Nature has revealed insights into the modulation of conformational dynamics of the µ-opioid receptor (µOR) by ligand efficacy, offering potential for improved pain management therapeutics. The research identified various receptor conformations and their impact on G-protein binding and β-arrestin-1 interaction, shedding light on the development of safer therapeutic profiles for pain management.
Understanding Ketamine and How It Works
Learn what ketamine is and how it works in the brain. Discover how ketamine therapy can help with depression and anxiety. Get insights from experts on the use of ketamine and its effects.