Groundbreaking Discovery Reveals Critical Role of DNA Loops in Gene Repression
USC Stem Cell scientists have made a groundbreaking discovery that could reshape our understanding of how DNA functions and influences human health. The study, led by Oliver Bell, revealed the critical role that DNA loops play in gene repression. Published…
Machine Learning Revolutionizes Drug Discovery in Cancer Treatment
Machine learning has revolutionized the field of drug discovery, leading to the identification of numerous previously unknown drug targets for various types of cancer. A recent study published in Cancer Cell by scientists from the Wellcome Sanger Institute has unveiled…
Unearthing Individual-Level Mutation Risk Patterns
Unearthing individual-level mutation risk patterns Reviewed Jan 10 2024 Mutations, which occur continuously in every cell of our bodies, are a key contributor to cancer, ageing, and neurodegeneration. While exposure to mutagenic chemicals, or mistakes in cellular processes during DNA…
Gene-Editing Breakthrough Offers Hope for Sickle-Cell Disease Patients
The year 2024 marks a significant milestone in the field of biotechnology and health as the first gene-editing treatment has made its breakthrough, offering hope to patients suffering from sickle-cell disease. This revolutionary treatment, utilizing the potent DNA-snipping technology known…
Scientists Grow First Brain Organoids from Human Fetal Tissue, Opening New Window into Brain Development
Scientists have achieved a significant milestone in brain research by growing the first brain organoids from human fetal tissue. These brainlike structures, called organoids, could provide a realistic model to study developmental disorders and brain cancers, offering a window into…
Researchers Study Molecular Freight Elevator in Pathogenic Bacteria
How does a molecular freight elevator work? Bonn researchers study an important membrane transport mechanism in pathogenic bacteria UNIVERSITATSKLINIKUM BONN – Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior…
Protein structures signal fresh targets for anticancer drugs
Protein structures signal fresh targets for anticancer drugs Cell replication in our bodies is triggered by a cascade of molecular signals transmitted between proteins. Compounds that block these signals when they run amok show potential as cancer drugs. Scientists have…
Enhancing Organoid Culture Optimization and the Importance of Growth Factor Bioactivity and Reagent Consistency
An organoid is a simplified and smaller version of an organ produced in vitro. Organoids resemble the cellular architecture and composition of the original tissue and demonstrate functional similarities. This article talks about enhancing organoid culture optimization and the importance…
Akoya Biosciences and Enable Medicine Announce Deployment of MaxFuse Algorithm for Integrating Multiomic Single-Cell and Spatial Datasets
Akoya Biosciences, Inc., in collaboration with Enable Medicine, has announced the deployment of MaxFuse, an advanced algorithm co-developed by Dr. Garry Nolan for integrating multiomic single-cell and spatial datasets. The algorithm enables the matching and integration of datasets from spatial…
New Study Reveals 11,000 Vital Genetic Switches in Every Cell Type
Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code. New evidence challenges the simplistic view that cis-regulatory elements (CREs) are mere on/off switches for genes, emphasizing their…