Protein structures signal fresh targets for anticancer drugs
Protein structures signal fresh targets for anticancer drugs Cell replication in our bodies is triggered by a cascade of molecular signals transmitted between proteins. Compounds that block these signals when they run amok show potential as cancer drugs. Scientists have…
Enhancing Organoid Culture Optimization and the Importance of Growth Factor Bioactivity and Reagent Consistency
An organoid is a simplified and smaller version of an organ produced in vitro. Organoids resemble the cellular architecture and composition of the original tissue and demonstrate functional similarities. This article talks about enhancing organoid culture optimization and the importance…
Akoya Biosciences and Enable Medicine Announce Deployment of MaxFuse Algorithm for Integrating Multiomic Single-Cell and Spatial Datasets
Akoya Biosciences, Inc., in collaboration with Enable Medicine, has announced the deployment of MaxFuse, an advanced algorithm co-developed by Dr. Garry Nolan for integrating multiomic single-cell and spatial datasets. The algorithm enables the matching and integration of datasets from spatial…
New Study Reveals 11,000 Vital Genetic Switches in Every Cell Type
Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code. New evidence challenges the simplistic view that cis-regulatory elements (CREs) are mere on/off switches for genes, emphasizing their…
Local Siblings with Genetic Disease Defy the Odds Thanks to Breakthrough Drug
Local Siblings with Genetic Disease Defy the Odds Thanks to Breakthrough Drug A heartwarming story of two siblings with a rare genetic disease defying the odds has captured the attention of many. Thanks to a breakthrough drug, these local siblings…
New Treatment for Cancer Targets Chaotic Protein MYC
A groundbreaking new treatment for cancer has been developed by researchers at the University of California-Riverside. The treatment targets the chaotic protein, MYC, which is linked to 75% of all cancer cases in humans. MYC, known for its pivotal role…
Groundbreaking Study Sheds Light on Synaptonemal Complex in Nematode C. elegans
This week in the world of science, a groundbreaking study has been published shedding light on the intricate interactions of the synaptonemal complex in the nematode C. elegans. Conducted by biologists at the University of Utah, the research has identified…
New High-Resolution Technique Developed for Identifying Potential Therapeutic Targets on Proteins in Living Cells
Scientists from Scripps Research have developed a new high-resolution technique for identifying potential therapeutic targets on proteins in living cells. This innovative method could lead to the development of more targeted and effective therapeutics for treating human diseases. The new…
Study Reveals Unique Characteristics of Human Purkinje Cells in the Cerebellum
Recent research has shed light on the morphological and physiological characteristics of human Purkinje cells (PCs), a crucial type of neuron in the cerebellum. While these cells have been extensively studied in rodents, our understanding of them in humans has…
New Method Using Aminocyanine Molecules to Destroy Cancer Cells
Scientists have made a groundbreaking discovery in the fight against cancer, as they have found a new method to destroy cancer cells in the lab. By stimulating aminocyanine molecules with near-infrared light, researchers were able to cause these molecules to…