Breakthrough in Acute Leukaemia Treatment
Recent research published in Nature reveals a potential breakthrough in acute leukaemia treatment, focusing on the role of PI3Kγ in cancer cells. The study identifies a dependency on the PI3Kγ complex in high-risk acute leukaemias, with promising results from treatment with a selective PI3Kγ inhibitor eganelisib. Combining eganelisib with cytarabine shows improved survival rates, offering hope for patients with acute leukaemia.
Protein structures signal fresh targets for anticancer drugs
Protein structures signal fresh targets for anticancer drugs Cell replication in our bodies is triggered by a cascade of molecular signals transmitted between proteins. Compounds that block these signals when they run amok show potential as cancer drugs. Scientists have…
Study Reveals Need for Personalized Approach in Treating Allergy and Inflammatory Disorders
A new study published in the Jan. 4, 2024, print issue of Cell sheds light on the tissue-specific actions of JAK1, revealing a potential need for a more nuanced therapeutic approach in treating allergy and inflammatory disorders. Conducted by researchers…