Bredt’s rule

Breakthrough in Organic Chemistry: New Strategies for Synthesizing Anti-Bredt Olefins

Researchers at the University of California have developed groundbreaking strategies to synthesize anti-Bredt olefins, overcoming Bredt’s rule limitations. This innovation opens new pathways for complex molecular structures, crucial for drug development. Neil Garg’s team successfully created enantiomerically enriched anti-Bredt olefins, paving the way for novel applications in pharmaceuticals and organic synthesis.