Enobosarm Shows Promising Antitumor Activity in ER-Positive, HER2-Negative Advanced Breast Cancer

A recent study published in The Lancet Oncology has shown promising antitumor activity of enobosarm in patients with ER-positive, HER2-negative advanced breast cancer. The study assessed the activity and safety of enobosarm in women with previously treated locally advanced or metastatic breast cancer, with results showing potential benefits but also some drug-related adverse events. The study was funded by GTx, the original developer of enobosarm, and has implications for the potential role of androgen receptor modulation in cancer therapy.