Apolipoprotein E

New Genetic Variant Identified as Clear Cause of Alzheimer’s Disease

New research has identified the APOE4 gene variant as a clear cause of Alzheimer’s disease, with individuals having two copies at increased risk. Dr. Juan Fortea’s study suggests that having two copies of APOE4 may not only increase the chances of developing Alzheimer’s but could actually be a direct cause of the disease. This discovery opens up avenues for targeted research and interventions, potentially leading to early diagnosis and tailored treatments for affected individuals.

Study Reveals APOE4 Homozygosity as Distinct Genetic Form of Alzheimer’s Disease

A new study reveals that APOE4 homozygosity represents a distinct genetic form of Alzheimer’s disease, with near-full penetrance of AD biology, earlier symptom onset, and specific biomarker changes. Individualized prevention strategies and treatments are emphasized for this unique genetic profile.

New Study Suggests Fat Droplets in Brain Cells May Be Key to Fighting Alzheimer’s

Recent study suggests that fat droplets within brain cells could be a key factor in Alzheimer’s disease development. Targeting these droplets may lead to more effective treatments, opening up a new avenue for therapeutic development. This sheds new light on the potential role of fat deposits in brain cells in causing Alzheimer’s, offering a fresh perspective for future research and treatment development.