Adrenal gland

Promising Results for CAH Patients Treated with Crinecerfont Revealed in Study

A recent study published in the New England Journal of Medicine has revealed promising results for patients with congenital adrenal hyperplasia (CAH) who were treated with crinecerfont. The research showed that crinecerfont led to a significant decrease in daily glucocorticoid dose compared to a placebo. The study, presented at the annual meeting of the Endocrine Society, demonstrated a 27.3% reduction in glucocorticoid dose with crinecerfont therapy, highlighting its potential benefits for adults with classic CAH.

New Hormone-Producing Cell Linked to Monogamous Behavior in Mice

A recent study published in Nature by scientists at Columbia University’s Zuckerman Institute reveals the discovery of a new hormone-producing cell in monogamous mice, shedding light on potential links to nurturing behavior and monogamy. The unique adrenal cell type produces 20⍺-OHP, enhancing nurturing behavior in mice and offering insights into human parental behavior and postpartum depression treatments. This groundbreaking research compares the mating behaviors of deer mice and oldfield mice, highlighting the role of hormones in shaping behavior and providing valuable insights into the mechanisms underlying monogamy.