Reservoir Neuroscience has recently completed a $4M financing round to support its development of new therapies for neurodegenerative diseases. The initiative, led by Kizoo Technology Capital, aims to focus on brain health by developing a novel class of drug compounds designed to restore health to the brain’s blood vessels in order to rejuvenate the aging brain.
Reservoir Neuroscience, co-founded by Aaron Friedman and Vlad Senatorov, PhD neuroscientists from UC Berkeley, has a unique approach to neurodegeneration, focusing on understanding how aging blood vessels affect brain health. The company’s goal is to develop the first drug that specifically targets vascular disease as a new way to restore brain health during natural aging and in aging-related disease.
The company’s research has shown that a majority of the aging population develops vascular decline as early as middle age, making vascular pathology one of the first and most prevalent signs of brain disease. Using an innovative organ-on-chip technology to grow human blood vessels and study vascular aging, Reservoir discovered and developed a first-in-kind compound that reverses disease in blood vessels and repairs the damaged blood-brain barrier.
Dr. Friedman, CEO of Reservoir Neuroscience, expressed optimism about the approach, stating, “By treating the underlying vascular problems that most patients inevitably develop through aging, we are addressing the single greatest risk factor for developing neurodegenerative disease. We believe this approach to rejuvenating the aging brain will be effective not only as a single therapy, but also has broader potential for brain health and systemic benefits in a wide variety of aging-related diseases.”
Patrick Burgermeister, partner of Kizoo Technology Capital and new board member of Reservoir Neuroscience, also expressed confidence in the initiative, saying, “We believe that Reservoir’s novel approach to restoring the health of the brain’s blood vessels, while also repairing the blood-brain barrier, has the potential to address the root cause of several neurological pathologies.”
Reservoir Neuroscience is an early-stage, San Francisco Bay Area venture-backed biotech company advancing a novel therapy to reverse brain vascular pathology in aging and neurodegenerative diseases.
