Preoxygenation is a critical step in preparing for intubation procedures, aiming to optimize oxygen levels in the body and prevent potential complications during airway management. A recent study, the Pragmatic Trial Examining Oxygenation Prior to Intubation (PREOXI trial), has shed light on the effectiveness of using BiPAP (noninvasive positive pressure ventilation) for preoxygenation.

The PREOXI trial, conducted in multiple emergency departments and ICUs in the United States, focused on critically ill adult patients undergoing intubation with sedation and a laryngoscope. The study compared preoxygenation techniques using NIPPV versus traditional oxygen masks.

Patients in the intervention group received preoxygenation with NIPPV, following specific protocol guidelines such as setting FiO2 at 100%, expiratory and inspiratory pressures, and respiratory rate. On the other hand, the comparison group underwent preoxygenation with oxygen masks, with the choice between nonrebreather and BVM left to the clinician’s discretion.

The results of the PREOXI trial are eagerly awaited as they have the potential to influence clinical practices in the management of preoxygenation before intubation procedures. Stay tuned for further updates on this groundbreaking study.