Enzyme Checkpoint Identified in Tumor-Associated Macrophages
A recent study has identified an enzyme, phosphoglycerate dehydrogenase (PHGDH), as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs), affecting tumor growth. Targeting PHGDH could be a new approach in cancer treatment, potentially improving the effectiveness of clinical immunotherapies. The study utilized innovative methods, including AI and machine learning, to diagnose metabolic markers and identify checkpoints, leading to the discovery of the metabolic checkpoint in macrophage polarization.
New Study Reveals Link Between Sense of Touch and Perception of Time
A recent study published in Nature Communications has revealed a fascinating link between the somatosensory cortex, responsible for processing sensory information from the skin, and our perception of the duration of tactile experiences. Led by Professor Mathew Diamond of the International School for Advanced Studies (SISSA) in Italy, the research sheds new light on the relationship between the sense of touch and our perception of time, providing new insights into the complex relationship between touch and temporal experiences.
Misunderstood and Misdiagnosed: The Challenges of Living with ARFID in Wales
Individuals with ARFID in Wales, like 21-year-old Rachel from Pontypridd, are feeling misunderstood and misdiagnosed by healthcare professionals. ARFID, a little-known eating disorder, has seen a sevenfold rise in inquiries over the past five years, highlighting the urgent need for improved support and care. Beat’s chief executive Andrew Radford emphasizes the lack of information, research, and specialized treatment for ARFID, calling for enhanced resources and funding to address the growing prevalence of the disorder.
Boost Your Metabolism Naturally: 5 Foods to Turbocharge Your Energy
Learn how to boost your metabolism and increase your energy levels with these five metabolism-boosting foods. From spicy peppers to lean protein sources, each option ignites your calorie-burning potential. Discover how green tea, whole grains, and omega-3 fatty acids can support your fitness goals while keeping you feeling satisfied and energised throughout the day. Start fueling your metabolism for success today!
New HIV Prevention Injection Offered in South Africa
A groundbreaking new HIV prevention injection is now being offered to a limited number of individuals in South Africa, providing two months of protection with a single shot. Administered outside of clinical trials, the injection contains a long-acting formulation of the antiretroviral drug cabotegravir (CAB-LA), offering a more convenient and less painful alternative to traditional methods of prevention. Select individuals in South Africa have access to it through pilot projects such as the FAST PrEP study, aiming to introduce the injectable and gather valuable insights for future large-scale implementation.
The Role of Pharmacists in Integrating Pharmacogenomics Testing for Improved Medication Outcomes
Pharmacogenomics is increasingly important in clinical practice, and pharmacists are uniquely positioned to lead the way in integrating pharmacogenomics testing. The Clinical Pharmacogenetics Implementation Consortium (CPIC) has been providing guidelines for clinical care, including recommendations for cardiovascular medications such as clopidogrel. Pharmacists’ involvement in integrating pharmacogenomics testing into cardiology clinical practice holds significant potential to optimize medication therapy and improve patient outcomes.
Positive Cases of Avian Influenza Confirmed in Orlando
Orlando officials confirm positive cases of Avian Influenza after several swans were found dead at Lake Eola Park. City taking necessary precautions to limit spread of the virus, including disinfecting park surfaces and advising staff to take further precautions.
New Clinical Trial Shows Promise in Treating Certain Types of Mesothelioma
A recent clinical trial has shown promising results in the treatment of certain types of mesothelioma, a rare and aggressive form of cancer. The trial focused on a novel type of chemotherapy called pegargiminase, which has been found to improve the survival rates of patients with biphasic and sarcomatoid mesothelioma. The addition of pegargiminase to the standard chemotherapy treatment for nonepithelioid mesothelioma cases has emerged as a promising new approach, targeting tumors that lack argininosuccinate synthetase (ASS) expression. The results of this clinical trial represent a significant advancement in the treatment of mesothelioma, particularly for patients with biphasic and sarcomatoid cell types.
Doctor Warns Against Heating Food in Plastic Containers in Microwave
Learn about the potential health risks of heating up food in plastic containers in the microwave. Doctor Saurabh Sethi warns about hormone-disrupting compounds like BPA contaminating food when heated. Research suggests that even BPA-free plastics can still pose a risk when microwaved. Consider using glass or ceramic containers instead to avoid potential health issues.
Healthy Hydration: Alternatives to Water
Learn about healthy alternatives to water for staying hydrated, including herbal teas, coconut water, and infused water with fruit. Professional sports dietitian Jordan Mazur emphasizes the importance of finding a drink that individuals enjoy to make it easier to stay hydrated. Avoid alcohol, sugary drinks, and caffeinated beverages for optimal hydration and overall well-being.