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First UK Patients Receive Innovative mRNA Therapy for Cancer in Global Trial

First UK patients have received an innovative mRNA therapy for cancer known as mRNA-4359, as part of a global trial. The therapy aims to help the body recognize and fight cancer cells by presenting common markers of tumors to the patient’s immune system. The Mobilize trial, conducted in partnership between Imperial College London and Imperial College Healthcare NHS Trust, is evaluating the safety and potential of the therapy in treating melanoma, lung cancer, and other ‘solid tumor’ cancers. Researchers are hopeful that the therapy may lead to a new treatment option for challenging-to-treat cancers if proven to be safe and effective.

Dengue Outbreak Impacting Costa Rica and the Americas

Costa Rica continues to battle an outbreak of dengue fever, with over 1,000 cases reported so far in 2024. The Pan American Health Organization has issued various dengue Risk Assessments, highlighting the endemic nature of the virus in most countries of South America, Central America, and the Caribbean. The CDC has also reported dengue outbreaks in U.S. territories. However, there is hope on the horizon with two vaccines currently in use in the Americas and several vaccine candidates in development.

Rise in Premature Births Linked to Synthetic Chemicals in Food Packaging and Personal Care Products

A new study suggests that synthetic chemicals found in food packaging and personal care products, known as phthalates, could be contributing to the rise in premature births. These ‘everywhere chemicals’ have been shown to disrupt hormones and impact the functioning of the placenta, potentially triggering preterm labor. The study identified a specific phthalate, DEHP, commonly found in food packaging, as a significant contributor to preterm births, raising concerns about their potential impact on public health.

Rumored Nintendo Direct Broadcast Sparks Excitement and Speculation

Rumors of a new Nintendo Direct airing next week have sparked excitement among fans, with speculations about potential announcements including Switch ports for The Legend of Zelda and Metroid Prime 4. As the rumored date approaches, fans eagerly await official confirmation from Nintendo, reflecting the enthusiasm and curiosity within the gaming community for upcoming releases and announcements.

CD Projekt Red Announces Veteran Developers for Cyberpunk 2077 Sequel, Project Orion

CD Projekt Red has announced the appointment of veteran developers to work on its Cyberpunk 2077 sequel, codenamed Project Orion. The core team members behind Cyberpunk 2077 have moved to North America to lead the development of the sequel, with the company’s North American arm leading the development. The studio also revealed the addition of experienced developers from Amazon Games, Blizzard, Ubisoft, and more. CD Projekt stated that Project Orion is in the ‘conceptual design’ phase and is currently hiring for various positions at its North American studios.

Google Maps on Android Auto Now Displaying 3D Buildings More Widely

Google Maps on Android Auto now displays 3D buildings by default, enhancing the navigation experience. Users can turn off this feature in settings. The addition of 3D buildings provides a more visually engaging experience for drivers, part of Google’s ongoing efforts to improve navigation services.

Tencent Plans Mobile Version of Elden Ring with Loot Boxes and Microtransactions

Elden Ring, the highly anticipated game by FromSoftware, may be the next target for mobile loot boxes and microtransactions by Tencent. Despite setbacks with previous mobile game versions, Tencent is determined to find new hits in the mobile gaming market, with plans for a free-to-play mobile version of Elden Ring with in-app purchases. This raises concerns about the impact on the game’s design and the gaming community as the industry shifts towards monetization-driven models.

How to Achieve the Best Ending in Persona 3 Reload

Learn how to achieve the best ending in Persona 3 Reload with this guide. Find out the crucial decision that will lead to the favorable outcome without encountering spoilers. Discover the single pivotal choice that determines the game’s ending and how to navigate it to secure the best possible outcome.

Huawei Pocket S2: What to Expect from the Successor to the Cheapest Foldable Phone in 2022

Huawei is rumored to be releasing the Pocket S2, a clamshell phone that may not change much on the outside but is expected to bring 5G capabilities and a triple camera setup. The device is speculated to feature a Kirin 9000s chipset, a 4,520mAh battery, and 66W wired fast charging. The original Pocket S was praised for its impressive specs at a lower price point, making the upcoming Pocket S2 an anticipated release.

JPL Announces Significant Workforce Reduction

JPL, managed by Caltech and funded by NASA, announces a significant reduction in workforce due to lower budget and lack of FY24 appropriation from Congress. Approximately 530 employees and 40 contractors will be impacted, with the aim of protecting against deeper cuts later in the fiscal year.